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Nucleoplasmic localization of prelamin A: implications for prenylation-dependent lamin A assembly into the nuclear lamina.

The synthesis of the nuclear lamina protein lamin A requires the prenylation-dependent processing of its precursor protein, prelamin A. Unlike p21ras, which undergoes similar initial posttranslational modifications, maturation of lamin A results in the proteolytic removal of the prenylated portion o...

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Bibliographic Details
Main Authors: Lutz, R J, Trujillo, M A, Denham, K S, Wenger, L, Sinensky, M
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC48791/
https://ncbi.nlm.nih.gov/pubmed/1557405
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