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Nucleoplasmic localization of prelamin A: implications for prenylation-dependent lamin A assembly into the nuclear lamina.

The synthesis of the nuclear lamina protein lamin A requires the prenylation-dependent processing of its precursor protein, prelamin A. Unlike p21ras, which undergoes similar initial posttranslational modifications, maturation of lamin A results in the proteolytic removal of the prenylated portion o...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lutz, R J, Trujillo, M A, Denham, K S, Wenger, L, Sinensky, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.3000
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