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Structural characterization of the C-terminal coiled coil domains of wild-type and kidney disease associated mutants of Apolipoprotein L1

Trypanosomes that cause sleeping sickness endocytose Apolipoprotein L1 (APOL1)-containing Trypanolytic Factors from human serum, leading to trypanolytic death through generation of APOL1-associated lytic pores in trypanosomal membranes. The trypanosome T. brucei rhodesiense counteracts trypanolysis...

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Publicat a:FEBS J
Autors principals: Sharma, Alok K., Friedman, David J., Pollak, Martin R., Alper, Seth L.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879057/
https://ncbi.nlm.nih.gov/pubmed/26945671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13706
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