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Lacosamide modulates interictal spiking and high-frequency oscillations in a model of mesial temporal lobe epilepsy

OBJECTIVE: Nearly one third of patients presenting with mesial temporal lobe epilepsy (MTLE), the most prevalent lesion-related epileptic disorder in adulthood, do not respond to currently available antiepileptic medications. Thus, there is a need to identify and characterize new antiepileptic drugs...

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Bibliographic Details
Published in:Epilepsy Res
Main Authors: Behr, Charles, Lévesque, Maxime, Ragsdale, David, Avoli, Massimo
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878889/
https://ncbi.nlm.nih.gov/pubmed/26220372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2015.05.006
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