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Synaptotagmin-1 C2B domain interacts simultaneously with SNAREs and membranes to promote membrane fusion
Synaptotagmin-1 (Syt1) acts as a Ca(2+) sensor for neurotransmitter release through its C2 domains. It has been proposed that Syt1 promotes SNARE-dependent fusion mainly through its C2B domain, but the underlying mechanism is poorly understood. In this study, we show that the C2B domain interacts si...
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| Publicado no: | eLife |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878868/ https://ncbi.nlm.nih.gov/pubmed/27083046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14211 |
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