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Modeling the Study of DNA Damage Responses in Mice

Damaged DNA has a profound impact on mammalian health and overall survival. In addition to being the source of mutations that initiate cancer, the accumulation of toxic amounts of DNA damage can cause severe developmental diseases and accelerate ageing. Therefore, understanding how cells respond to...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: Specks, Julia, Nieto-Soler, Maria, Lopez-Contreras, Andres J, Fernandez-Capetillo, Oscar
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878652/
https://ncbi.nlm.nih.gov/pubmed/25636482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2297-0_21
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