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Modeling the Study of DNA Damage Responses in Mice

Damaged DNA has a profound impact on mammalian health and overall survival. In addition to being the source of mutations that initiate cancer, the accumulation of toxic amounts of DNA damage can cause severe developmental diseases and accelerate ageing. Therefore, understanding how cells respond to...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Specks, Julia, Nieto-Soler, Maria, Lopez-Contreras, Andres J, Fernandez-Capetillo, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878652/
https://ncbi.nlm.nih.gov/pubmed/25636482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2297-0_21
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