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Anticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration

The aim of the present study was to investigate the in vitro and in vivo anticancer and apoptotic effects of taraxerol acetate in U87 human glioblastoma cells. The effects on cell cycle phase distribution, cell cycle-associated proteins, autophagy, DNA fragmentation and cell migration were assessed....

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: HONG, JING-FANG, SONG, YING-FANG, LIU, ZHENG, ZHENG, ZHAO-CONG, CHEN, HONG-JIE, WANG, SHOU-SEN
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878554/
https://ncbi.nlm.nih.gov/pubmed/27081915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5105
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