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Anticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration

The aim of the present study was to investigate the in vitro and in vivo anticancer and apoptotic effects of taraxerol acetate in U87 human glioblastoma cells. The effects on cell cycle phase distribution, cell cycle-associated proteins, autophagy, DNA fragmentation and cell migration were assessed....

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Библиографические подробности
Опубликовано в: :Mol Med Rep
Главные авторы: HONG, JING-FANG, SONG, YING-FANG, LIU, ZHENG, ZHENG, ZHAO-CONG, CHEN, HONG-JIE, WANG, SHOU-SEN
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878554/
https://ncbi.nlm.nih.gov/pubmed/27081915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5105
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