Efficient analysis of mouse genome sequences reveal many nonsense variants

Genetic polymorphisms in coding genes play an important role when using mouse inbred strains as research models. They have been shown to influence research results, explain phenotypical differences between inbred strains, and increase the amount of interesting gene variants present in the many avail...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Steeland, Sophie, Timmermans, Steven, Van Ryckeghem, Sara, Hulpiau, Paco, Saeys, Yvan, Van Montagu, Marc, Vandenbroucke, Roosmarijn E., Libert, Claude
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878497/
https://ncbi.nlm.nih.gov/pubmed/27147605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605076113
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