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Efficient analysis of mouse genome sequences reveal many nonsense variants

Genetic polymorphisms in coding genes play an important role when using mouse inbred strains as research models. They have been shown to influence research results, explain phenotypical differences between inbred strains, and increase the amount of interesting gene variants present in the many avail...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Steeland, Sophie, Timmermans, Steven, Van Ryckeghem, Sara, Hulpiau, Paco, Saeys, Yvan, Van Montagu, Marc, Vandenbroucke, Roosmarijn E., Libert, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878497/
https://ncbi.nlm.nih.gov/pubmed/27147605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605076113
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