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A Biocompatible Condensation Reaction for Labeling of Terminal Cysteines on Proteins
This communication describes a novel protein labeling method that uses a single amino-acid tag — N-terminal cysteine residue — and small-molecule probes carrying the cyanobenzothiazole unit for specific labeling of proteins in vitro and at the surface of live cells. This simple ligation reaction pro...
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| Veröffentlicht in: | Angew Chem Int Ed Engl |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878437/ https://ncbi.nlm.nih.gov/pubmed/19924746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200903627 |
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