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Bioluminescent nanosensors for protease detection based upon gold nanoparticle–luciferase conjugatesw

This communication reports the use of click chemistry to site-specifically conjugate bioluminescent Renilla luciferase proteins to gold nanoparticles (Au NPs) for sensing protease activity. The bioluminescent emission from luciferase was efficiently quenched by Au NPs, but significantly recovered af...

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Detalhes bibliográficos
Main Authors: Kim, Young-Pil, Daniel, Weston L., Xia, Zuyong, Xie, Hexin, Mirkin, Chad A., Rao, Jianghong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930333/
https://ncbi.nlm.nih.gov/pubmed/20024298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b915612g
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