Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study

BACKGROUND: Biomarkers are urgently needed to dissect the heterogeneity of prostate cancer between patients to improve treatment and accelerate drug development. We analysed blood mRNA expression arrays to identify patients with metastatic castration-resistant prostate cancer with poorer outcome. ME...

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Vydáno v:Lancet Oncol
Hlavní autoři: Olmos, David, Brewer, Daniel, Clark, Jeremy, Danila, Daniel C, Parker, Chris, Attard, Gerhardt, Fleisher, Martin, Reid, Alison H M, Castro, Elena, Sandhu, Shahneen K, Barwell, Lorraine, Oommen, Nikhil Babu, Carreira, Suzanne, Drake, Charles G, Jones, Robert, Cooper, Colin S, Scher, Howard I, de Bono, Johann S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878433/
https://ncbi.nlm.nih.gov/pubmed/23059046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(12)70372-8
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