Circulating Tumor Cell Biomarker Panel As an Individual-Level Surrogate for Survival in Metastatic Castration-Resistant Prostate Cancer

PURPOSE: Trials in castration-resistant prostate cancer (CRPC) need new clinical end points that are valid surrogates for survival. We evaluated circulating tumor cell (CTC) enumeration as a surrogate outcome measure. PATIENTS AND METHODS: Examining CTCs alone and in combination with other biomarker...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Scher, Howard I., Heller, Glenn, Molina, Arturo, Attard, Gerhardt, Danila, Daniel C., Jia, Xiaoyu, Peng, Weimin, Sandhu, Shahneen K., Olmos, David, Riisnaes, Ruth, McCormack, Robert, Burzykowski, Tomasz, Kheoh, Thian, Fleisher, Martin, Buyse, Marc, de Bono, Johann S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397279/
https://ncbi.nlm.nih.gov/pubmed/25800753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.55.3487
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