Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice

Diet-induced muscle insulin resistance is associated with expansion of extracellular matrix (ECM) components, such as collagens, and the expression of collagen-binding integrin, α2β1. Integrins transduce signals from ECM via their cytoplasmic domains, which bind to intracellular integrin-binding pro...

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Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Kang, Li, Mokshagundam, Shilpa, Reuter, Bradley, Lark, Daniel S., Sneddon, Claire C., Hennayake, Chandani, Williams, Ashley S., Bracy, Deanna P., James, Freyja D., Pozzi, Ambra, Zent, Roy, Wasserman, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2016
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878430/
https://ncbi.nlm.nih.gov/pubmed/27207548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1434
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