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Diet-Induced Muscle Insulin Resistance Is Associated With Extracellular Matrix Remodeling and Interaction With Integrin α(2)β(1) in Mice

OBJECTIVE: The hypothesis that high-fat (HF) feeding causes skeletal muscle extracellular matrix (ECM) remodeling in C57BL/6J mice and that this remodeling contributes to diet-induced muscle insulin resistance (IR) through the collagen receptor integrin α(2)β(1) was tested. RESEARCH DESIGN AND METHO...

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Detalhes bibliográficos
Main Authors: Kang, Li, Ayala, Julio E., Lee-Young, Robert S., Zhang, Zhonghua, James, Freyja D., Neufer, P. Darrell, Pozzi, Ambra, Zutter, Mary M., Wasserman, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028340/
https://ncbi.nlm.nih.gov/pubmed/21270253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1116
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