Insulin Regulates Hepatic Triglyceride Secretion and Lipid Content via Signaling in the Brain

Hepatic steatosis is common in obesity and insulin resistance and results from a net retention of lipids in the liver. A key mechanism to prevent steatosis is to increase secretion of triglycerides (TG) packaged as VLDLs. Insulin controls nutrient partitioning via signaling through its cognate recep...

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Vydáno v:Diabetes
Hlavní autoři: Scherer, Thomas, Lindtner, Claudia, O’Hare, James, Hackl, Martina, Zielinski, Elizabeth, Freudenthaler, Angelika, Baumgartner-Parzer, Sabina, Tödter, Klaus, Heeren, Joerg, Krššák, Martin, Scheja, Ludger, Fürnsinn, Clemens, Buettner, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2016
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878422/
https://ncbi.nlm.nih.gov/pubmed/26861781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1552
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