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Pivotal Role of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 in Inflammatory Pulmonary Diseases

Mitogen-activated protein kinase (MAPK)-activated protein kinase (MK2) is exclusively regulated by p38 MAPK in vivo. Upon activation of p38 MAPK, MK2 binds with p38 MAPK, leading to phosphorylation of TTP, Hsp27, Akt and Cdc25 that are involved in regulation of various essential cellular functions....

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Bibliografiske detaljer
Udgivet i:Curr Protein Pept Sci
Main Authors: Qian, Feng, Deng, Jing, Wang, Gang, Ye, Richard D., Christman, John W.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878395/
https://ncbi.nlm.nih.gov/pubmed/26119506
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