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High immunogenicity of plant-produced candidate influenza vaccine based on the M2e peptide fused to flagellin

The ectodomain of the conserved influenza matrix protein M2 (M2e) is a promising target for the development of a universal influenza vaccines. Immunogenicity of M2e could be enhanced by its fusion to bacterial flagellin, the ligand for Toll-like receptor 5. Previously we reported the transient expre...

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Dettagli Bibliografici
Pubblicato in:Bioengineered
Autori principali: Mardanova, Eugenia S., Kotlyarov, Roman Y., Kuprianov, Victor V., Stepanova, Liudmila A., Tsybalova, Liudmila M., Lomonossoff, George P., Ravin, Nikolai V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878292/
https://ncbi.nlm.nih.gov/pubmed/26710263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2015.1126017
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