Rapid high-yield expression of a candidate influenza vaccine based on the ectodomain of M2 protein linked to flagellin in plants using viral vectors

BACKGROUND: The extracellular domain of matrix protein 2 (M2e) of influenza A virus is a promising target for the development of a universal vaccine against influenza because M2e sequences are highly conserved among human influenza A strains. However, native M2e is poorly immunogenic, but its immuno...

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Vydáno v:BMC Biotechnol
Hlavní autoři: Mardanova, Eugenia S., Kotlyarov, Roman Y., Kuprianov, Victor V., Stepanova, Liudmila A., Tsybalova, Liudmila M., Lomonosoff, George P., Ravin, Nikolai V.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446962/
https://ncbi.nlm.nih.gov/pubmed/26022390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-015-0164-6
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