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Autophagy deficiency in β cells blunts incretin-induced suppression of glucagon release from α cells

Incretin-based therapy such as GLP-1 receptor agonists and DPP-4 inhibitors for type 2 diabetes mellitus is characterized by glucose-dependent insulin secretion and glucose-inhibited glucagon secretion. Recently, autophagy deficiency in islet β cells has been shown to contribute to the pathogenesis...

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Detalhes bibliográficos
Publicado no:Islets
Main Authors: Kim, Min Joo, Choi, Ok Kyong, Chae, Kyung Sil, Lee, Hakmo, Chung, Sung Soo, Ham, Dong-Sik, Kim, Ji-Won, Yoon, Kun-Ho, Park, Kyong Soo, Jung, Hye Seung
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878271/
https://ncbi.nlm.nih.gov/pubmed/26744903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2015.1129096
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