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Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma

PURPOSE: Reports detailing the prognostic impact of TP53 mutations in medulloblastoma offer conflicting conclusions. We resolve this issue through the inclusion of molecular subgroup profiles. PATIENTS AND METHODS: We determined subgroup affiliation, TP53 mutation status, and clinical outcome in a d...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Zhukova, Nataliya, Ramaswamy, Vijay, Remke, Marc, Pfaff, Elke, Shih, David J.H., Martin, Dianna C., Castelo-Branco, Pedro, Baskin, Berivan, Ray, Peter N., Bouffet, Eric, von Bueren, André O., Jones, David T.W., Northcott, Paul A., Kool, Marcel, Sturm, Dominik, Pugh, Trevor J., Pomeroy, Scott L., Cho, Yoon-Jae, Pietsch, Torsten, Gessi, Marco, Rutkowski, Stefan, Bognar, Laszlo, Klekner, Almos, Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Eberhart, Charles G., Fevre-Montange, Michelle, Fouladi, Maryam, French, Pim J., Kros, Max, Grajkowska, Wieslawa A., Gupta, Nalin, Weiss, William A., Hauser, Peter, Jabado, Nada, Jouvet, Anne, Jung, Shin, Kumabe, Toshihiro, Lach, Boleslaw, Leonard, Jeffrey R., Rubin, Joshua B., Liau, Linda M., Massimi, Luca, Pollack, Ian F., Shin Ra, Young, Van Meir, Erwin G., Zitterbart, Karel, Schüller, Ulrich, Hill, Rebecca M., Lindsey, Janet C., Schwalbe, Ed C., Bailey, Simon, Ellison, David W., Hawkins, Cynthia, Malkin, David, Clifford, Steven C., Korshunov, Andrey, Pfister, Stefan, Taylor, Michael D., Tabori, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878050/
https://ncbi.nlm.nih.gov/pubmed/23835706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.48.5052
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