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Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy

The term epigenetics is defined as heritable changes in gene expression that are not due to alterations of the DNA sequence. In the last years, it has become more and more evident that dysregulated epigenetic regulatory processes have a central role in cancer onset and progression. In contrast to DN...

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Bibliografische gegevens
Gepubliceerd in:Clin Epigenetics
Hoofdauteurs: Morera, Ludovica, Lübbert, Michael, Jung, Manfred
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877953/
https://ncbi.nlm.nih.gov/pubmed/27222667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0223-4
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