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Targeting histone methyltransferase and demethylase in acute myeloid leukemia therapy

Acute myeloid leukemia (AML) is a clonal disorder of myeloid progenitors characterized by the acquisition of chromosomal abnormalities, somatic mutations, and epigenetic changes that determine a consistent degree of biological and clinical heterogeneity. Advances in genomic technologies have increas...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Castelli, Germana, Pelosi, Elvira, Testa, Ugo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749389/
https://ncbi.nlm.nih.gov/pubmed/29343972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S145971
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