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Integrated Microfluidic Isolation of Aptamers Using Electrophoretic Oligonucleotide Manipulation
We present a microfluidic approach to integrated isolation of DNA aptamers via systematic evolution of ligands by exponential enrichment (SELEX). The approach employs a microbead-based protocol for the processes of affinity selection and amplification of target-binding oligonucleotides, and an elect...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4877600/ https://ncbi.nlm.nih.gov/pubmed/27217242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26139 |
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