A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A

The regulation of stability is particularly crucial for unstable proteins in cells. However, a convenient and unbiased method of identifying regulators of protein stability remains to be developed. Recently, a genome-scale CRISPR-Cas9 library has been established as a genetic tool to mediate loss-of...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Discov
Κύριοι συγγραφείς: Wu, Yuanzhong, Zhou, Liwen, Wang, Xin, Lu, Jinping, Zhang, Ruhua, Liang, Xiaoting, Wang, Li, Deng, Wuguo, Zeng, Yi-Xin, Huang, Haojie, Kang, Tiebang
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2016
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877570/
https://ncbi.nlm.nih.gov/pubmed/27462461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.14
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