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De novo sequencing and variant calling with nanopores using PoreSeq

The single-molecule accuracy of nanopore sequencing has been an area of rapid academic and commercial advancement, but remains challenging for the de novo analysis of genomes. We introduce here a novel algorithm for the error correction of nanopore data, utilizing statistical models of the physical...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Biotechnol
Egile Nagusiak: Szalay, Tamas, Golovchenko, Jene A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877053/
https://ncbi.nlm.nih.gov/pubmed/26352647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3360
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