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De novo sequencing and variant calling with nanopores using PoreSeq
The single-molecule accuracy of nanopore sequencing has been an area of rapid academic and commercial advancement, but remains challenging for the de novo analysis of genomes. We introduce here a novel algorithm for the error correction of nanopore data, utilizing statistical models of the physical...
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| Veröffentlicht in: | Nat Biotechnol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4877053/ https://ncbi.nlm.nih.gov/pubmed/26352647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3360 |
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