Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients

Cross-sectional relationships were examined between regional brain volumes and mitochondrial DNA (mtDNA) 8-hydroxy-2-deoxyguanosine (8-oxo-dG) in peripheral blood mononuclear cells (PBMCs) of 47 HIV patients [mean age 51 years; 81% with HIV RNA ≤50 copies/mL] on combination antiretroviral therapy. T...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mitochondrion
Hlavní autoři: Kallianpur, Kalpana J., Gerschenson, Mariana, Mitchell, Brooks I., LiButti, Daniel E., Umaki, Tracie M., Ndhlovu, Lishomwa C., Nakamoto, Beau K., Chow, Dominic C., Shikuma, Cecilia M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877028/
https://ncbi.nlm.nih.gov/pubmed/26923169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2016.02.006
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky