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Inhibition of Cardiac Kir Current (I(K1)) by Protein Kinase C Critically Depends on PKCβ and Kir2.2
BACKGROUND: Cardiac inwardly rectifying Kir current (I(K1)) mediates terminal repolarisation and is critical for the stabilization of the diastolic membrane potential. Its predominant molecular basis in mammalian ventricle is heterotetrameric assembly of Kir2.1 and Kir2.2 channel subunits. It has be...
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| Udgivet i: | PLoS One |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4877014/ https://ncbi.nlm.nih.gov/pubmed/27214373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156181 |
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