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WS6 induces both alpha and beta cell proliferation without affecting differentiation or viability

Agents that stimulate human pancreatic beta cell proliferation are needed to improve diabetes mellitus treatment. Recently, a small molecule, WS6, was observed to stimulate human beta cell proliferation. However, little is known about its other effects on human islets. To better understand the role...

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Bibliografiske detaljer
Udgivet i:Endocr J
Main Authors: Boerner, Brian P., George, Nicholas M., Mir, Shakeel U.R., Sarvetnick, Nora E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876955/
https://ncbi.nlm.nih.gov/pubmed/25739404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1507/endocrj.EJ14-0449
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