TGF-β Superfamily Member Nodal Stimulates Human β-Cell Proliferation While Maintaining Cellular Viability

In an effort to expand human islets and enhance allogeneic islet transplant for the treatment of type 1 diabetes, identifying signaling pathways that stimulate human β-cell proliferation is paramount. TGF-β superfamily members, in particular activin-A, are likely involved in islet development and ma...

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Bibliografiska uppgifter
Huvudupphovsmän: Boerner, Brian P., George, Nicholas M., Targy, Natalie M., Sarvetnick, Nora E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2013
Ämnen:
Diabetes-Insulin-Glucagon-Gastrointestinal
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800770/
https://ncbi.nlm.nih.gov/pubmed/23970788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1197
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