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TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis

To evaluate the role of TCF7L2, a key regulator of glucose homeostasis, in estradiol (E(2)) and progesterone (P(4))-modulated glucose metabolism, mouse insulinoma cells (MIN6) and human liver cancer cells (hepG2 and HUH7) were treated with physiological concentrations of E(2) or P(4) in the up- and...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Dong, Fengqin, Ling, Qi, Ye, Dan, Zhang, Zhe, Shu, Jing, Chen, Guoping, Fei, Yang, Li, Chengjiang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876840/
https://ncbi.nlm.nih.gov/pubmed/27108846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24859
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