Transcriptome Analysis of GVHD Reveals Aurora Kinase A as a Targetable Pathway for Disease Prevention

Graft versus host disease (GVHD) is the most common complication of hematopoietic stem cell transplant (HCT). However, our understanding of the molecular pathways that cause this disease remains incomplete, leading to inadequate treatment strategies. To address this, we measured the gene expression...

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Bibliografiske detaljer
Udgivet i:Sci Transl Med
Main Authors: Furlan, Scott N, Watkins, Benjamin, Tkachev, Victor, Flynn, Ryan, Cooley, Sarah, Ramakrishnan, Swetha, Singh, Karnail, Giver, Cindy, Hamby, Kelly, Stempora, Linda, Garrett, Aneesah, Chen, Jingyang, Betz, Kayla M, Ziegler, Carly G K, Tharp, Gregory K., Bosinger, Steven E., Promislow, Daniel E L, Miller, Jeffrey S, Waller, Edmund K., Blazar, Bruce R, Kean, Leslie S
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876606/
https://ncbi.nlm.nih.gov/pubmed/26606970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad3231
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