Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome

BACKGROUND: Altered plasma levels of protein C, thrombomodulin, and the endothelial protein C receptor are associated with poor clinical outcomes in patients with acute respiratory distress syndrome (ARDS). We hypothesized that common variants in these genes would be associated with mortality as wel...

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Publicat a:Crit Care
Autors principals: Sapru, Anil, Liu, Kathleen D., Wiemels, Joseph, Hansen, Helen, Pawlikowska, Ludmilla, Poon, Annie, Jorgenson, Eric, Witte, John S., Calfee, Carolyn S., Ware, Lorraine B., Matthay, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876559/
https://ncbi.nlm.nih.gov/pubmed/27215212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-016-1330-5
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