Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome

OBJECTIVE: Thombomodulin (TM) is an activator of protein C and a biomarker for endothelial injury. We hypothesized that (1) elevated plasma levels would be associated with clinical outcomes and (2) polymorphisms in the TM gene would be associated with plasma levels. PATIENTS: We studied 449 patients...

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Detalhes bibliográficos
Publicado no:Intensive Care Med
Main Authors: Sapru, Anil, Calfee, Carolyn S., Liu, Kathleen D., Kangelaris, Kirsten, Hansen, Helen, Pawlikowska, Ludmila, Ware, Lorraine B., Alkhouli, Mustafa F., Abbot, Jason, Matthay, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500527/
https://ncbi.nlm.nih.gov/pubmed/25643902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-015-3648-x
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