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Monoclonal regulatory T cells provide insights into T cell suppression

Regulatory T cells (Tregs) have a crucial role in maintaining lymphocyte homeostasis. However an understanding of how Tregs function at a cellular and molecular level has not yet been fully elucidated. Here, we make use of a T cell receptor (TCR) transgenic, Rag(−/−) mouse expressing a Forkhead-Box-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gubser, Céline, Schmaler, Mathias, Rossi, Simona W., Palmer, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876466/
https://ncbi.nlm.nih.gov/pubmed/27210828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25758
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