Underestimation of Risk of a BRCA1 or BRCA2 Mutation in Women With High-Grade Serous Ovarian Cancer by BRCAPRO: A Multi-Institution Study

PURPOSE: Identification of the 10% to 15% of patients with ovarian cancer who have germline BRCA1 or BRCA2 mutations is important for management of both patients and relatives. The BRCAPRO model, which estimates mutation likelihood based on personal and family cancer history, can inform genetic test...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Daniels, Molly S., Babb, Sheri A., King, Robin H., Urbauer, Diana L., Batte, Brittany A.L., Brandt, Amanda C., Amos, Christopher I., Buchanan, Adam H., Mutch, David G., Lu, Karen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2014
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876344/
https://ncbi.nlm.nih.gov/pubmed/24638001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.50.6055
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