Fulvestrant decreases anastrozole drug concentrations when taken concurrently by patients with metastatic breast cancer treated on SWOG study S0226

AIMS: In the SWOG S0226 trial the combination of anastrozole plus fulvestrant (n = 349) was superior to anastrozole alone (n = 345) in hormone receptor (HR)‐positive metastatic breast cancer. Here we report a pharmacokinetic subset analysis investigating a possible drug interaction between anastrozo...

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Foilsithe in:Br J Clin Pharmacol
Main Authors: Hertz, Daniel L., Barlow, William E., Kidwell, Kelley M., Albain, Kathy S., Vandenberg, Ted A., Dakhil, Shaker R., Tirumali, Nagendra R., Livingston, Robert B., Gralow, Julie, Hayes, Daniel F., Hortobagyi, Gabriel N., Mehta, Rita S., Rae, James M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Drug Interactions
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876171/
https://ncbi.nlm.nih.gov/pubmed/26859101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12904
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