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Benzolamide improves oxygenation and reduces acute mountain sickness during a high‐altitude trek and has fewer side effects than acetazolamide at sea level

Acetazolamide is the standard carbonic anhydrase (CA) inhibitor used for acute mountain sickness (AMS), however some of its undesirable effects are related to intracellular penetrance into many tissues, including across the blood–brain barrier. Benzolamide is a much more hydrophilic inhibitor, which...

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Bibliografische gegevens
Gepubliceerd in:Pharmacol Res Perspect
Hoofdauteurs: Collier, David J., Wolff, Chris B., Hedges, Anne‐Marie, Nathan, John, Flower, Rod J., Milledge, James S., Swenson, Erik R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876137/
https://ncbi.nlm.nih.gov/pubmed/27433337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.203
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