Benzolamide improves oxygenation and reduces acute mountain sickness during a high‐altitude trek and has fewer side effects than acetazolamide at sea level

Acetazolamide is the standard carbonic anhydrase (CA) inhibitor used for acute mountain sickness (AMS), however some of its undesirable effects are related to intracellular penetrance into many tissues, including across the blood–brain barrier. Benzolamide is a much more hydrophilic inhibitor, which...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharmacol Res Perspect
Main Authors: Collier, David J., Wolff, Chris B., Hedges, Anne‐Marie, Nathan, John, Flower, Rod J., Milledge, James S., Swenson, Erik R.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876137/
https://ncbi.nlm.nih.gov/pubmed/27433337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.203
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