Sclerostin Antibody (Scl-Ab) Improves Osteomalacia Phenotype in Dentin Matrix Protein 1(Dmp1) Knockout Mice with Little Impact on Serum Levels of Phosphorus and FGF23

Unlike treatments for most rickets, the treatment using 1,25-(OH)2 vitamin D3 has little efficacy on patients with hypophosphatemic rickets, a set of rare genetic diseases. Thus, understanding the local cause for osteomalacia in hypophosphatemic rickets and developing an effective treatment to resto...

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發表在:Matrix Biol
Main Authors: Ren, Yinshi, Han, Xianglong, Jing, Yan, Yuan, Baozhi, Ke, Huazhu, Liu, Min, Feng, Jian Q.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875883/
https://ncbi.nlm.nih.gov/pubmed/26721590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2015.12.009
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