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Cutting Edge: EZH2 promotes osteoclastogenesis by epigenetic silencing of the negative regulator IRF8

Osteoclasts are resorptive cells important for homeostatic bone remodeling and pathological bone resorption. Emerging evidence suggests an important role for epigenetic mechanisms in osteoclastogenesis. A recent study showed that epigenetic silencing of the negative regulator of osteoclastogenesis I...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Fang, Celestia, Qiao, Yu, Mun, Se Hwan, Lee, Min Joon, Murata, Koichi, Bae, Seyeon, Zhao, Baohong, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875854/
https://ncbi.nlm.nih.gov/pubmed/27183582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501466
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