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Cutting Edge: EZH2 promotes osteoclastogenesis by epigenetic silencing of the negative regulator IRF8

Osteoclasts are resorptive cells important for homeostatic bone remodeling and pathological bone resorption. Emerging evidence suggests an important role for epigenetic mechanisms in osteoclastogenesis. A recent study showed that epigenetic silencing of the negative regulator of osteoclastogenesis I...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Fang, Celestia, Qiao, Yu, Mun, Se Hwan, Lee, Min Joon, Murata, Koichi, Bae, Seyeon, Zhao, Baohong, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875854/
https://ncbi.nlm.nih.gov/pubmed/27183582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501466
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