Cutting Edge: EZH2 promotes osteoclastogenesis by epigenetic silencing of the negative regulator IRF8

Osteoclasts are resorptive cells important for homeostatic bone remodeling and pathological bone resorption. Emerging evidence suggests an important role for epigenetic mechanisms in osteoclastogenesis. A recent study showed that epigenetic silencing of the negative regulator of osteoclastogenesis I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Fang, Celestia, Qiao, Yu, Mun, Se Hwan, Lee, Min Joon, Murata, Koichi, Bae, Seyeon, Zhao, Baohong, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875854/
https://ncbi.nlm.nih.gov/pubmed/27183582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501466
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