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Cutting Edge: EZH2 promotes osteoclastogenesis by epigenetic silencing of the negative regulator IRF8

Osteoclasts are resorptive cells important for homeostatic bone remodeling and pathological bone resorption. Emerging evidence suggests an important role for epigenetic mechanisms in osteoclastogenesis. A recent study showed that epigenetic silencing of the negative regulator of osteoclastogenesis I...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Fang, Celestia, Qiao, Yu, Mun, Se Hwan, Lee, Min Joon, Murata, Koichi, Bae, Seyeon, Zhao, Baohong, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875854/
https://ncbi.nlm.nih.gov/pubmed/27183582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501466
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