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MicroRNA-155 suppresses autophagy in chondrocytes by modulating expression of autophagy proteins

OBJECTIVE: Autophagy dysfunction has been reported in osteoarthritis (OA) cartilage. The objective of this study was to investigate the role of microRNA-155 (miR-155), which is overexpressed in OA, in the regulation of autophagy in human chondrocytes. DESIGN: Rapamycin (50nM) and 2-deoxyglucose (2-D...

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Podrobná bibliografie
Vydáno v:Osteoarthritis Cartilage
Hlavní autoři: D’Adamo, Stefania, Alvarez-Garcia, Oscar, Muramatsu, Yuta, Flamigni, Flavio, Lotz, Martin K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875787/
https://ncbi.nlm.nih.gov/pubmed/26805019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.01.005
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