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MicroRNA-155 suppresses autophagy in chondrocytes by modulating expression of autophagy proteins
OBJECTIVE: Autophagy dysfunction has been reported in osteoarthritis (OA) cartilage. The objective of this study was to investigate the role of microRNA-155 (miR-155), which is overexpressed in OA, in the regulation of autophagy in human chondrocytes. DESIGN: Rapamycin (50nM) and 2-deoxyglucose (2-D...
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| 出版年: | Osteoarthritis Cartilage |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875787/ https://ncbi.nlm.nih.gov/pubmed/26805019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.01.005 |
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