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The Apoe(−/−) mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction
Atherosclerosis-prone apolipoprotein E-deficient (Apoe(−/−)) mice display poor lipoprotein clearance with subsequent accumulation of cholesterol ester-enriched particles in the blood, which promote the development of atherosclerotic plaques. Therefore, the Apoe(−/−) mouse model is well established f...
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| Publié dans: | J Transl Med |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875735/ https://ncbi.nlm.nih.gov/pubmed/27207171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0901-1 |
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