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A systematic, large-scale comparison of transcription factor binding site models

BACKGROUND: The modelling of gene regulation is a major challenge in biomedical research. This process is dominated by transcription factors (TFs) and mutations in their binding sites (TFBSs) may cause the misregulation of genes, eventually leading to disease. The consequences of DNA variants on TF...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Genomics
Hauptverfasser: Hombach, Daniela, Schwarz, Jana Marie, Robinson, Peter N., Schuelke, Markus, Seelow, Dominik
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875604/
https://ncbi.nlm.nih.gov/pubmed/27209209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2729-8
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