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A systematic, large-scale comparison of transcription factor binding site models

BACKGROUND: The modelling of gene regulation is a major challenge in biomedical research. This process is dominated by transcription factors (TFs) and mutations in their binding sites (TFBSs) may cause the misregulation of genes, eventually leading to disease. The consequences of DNA variants on TF...

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Bibliografiska uppgifter
I publikationen:BMC Genomics
Huvudupphovsmän: Hombach, Daniela, Schwarz, Jana Marie, Robinson, Peter N., Schuelke, Markus, Seelow, Dominik
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875604/
https://ncbi.nlm.nih.gov/pubmed/27209209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2729-8
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