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A systematic, large-scale comparison of transcription factor binding site models

BACKGROUND: The modelling of gene regulation is a major challenge in biomedical research. This process is dominated by transcription factors (TFs) and mutations in their binding sites (TFBSs) may cause the misregulation of genes, eventually leading to disease. The consequences of DNA variants on TF...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Hombach, Daniela, Schwarz, Jana Marie, Robinson, Peter N., Schuelke, Markus, Seelow, Dominik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875604/
https://ncbi.nlm.nih.gov/pubmed/27209209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2729-8
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