Autophagic UVRAG Promotes UV-induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase

Ultraviolet (UV)-induced DNA damage, a major risk factor for skin cancers, is primarily repaired by nucleotide excision repair (NER). UV-radiation Resistance Associated Gene (UVRAG) is a tumor suppressor involved in autophagy. It was initially isolated as a cDNA partially complementing UV sensitivit...

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Publicado no:Mol Cell
Main Authors: Yang, Yongfei, He, Shanshan, Wang, Qiaoxiu, Li, Fan, Kwak, Mi-Jeong, Chen, Sally, O’Connell, Douglas, Zhang, Tian, Pirooz, Sara Dolatshahi, Jeon, YongHeui, Chimge, Nyam-Osor, Frenkel, Baruch, Choi, Younho, Aldrovandi, Grace M., Oh, Byung-Ha, Yuan, Zengqiang, Liang, Chengyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875571/
https://ncbi.nlm.nih.gov/pubmed/27203177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.04.014
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